46. Johnathon Van Buskirk and Lisa Berg
Johnathon Van Buskirk and Lisa Berg of Michigan were both quite heavy for most of their lives. At the age of only 24, John weighed 420 pounds but had was already down 75 pounds when he met Lisa. This inspired her too.
Lisa had thought she would always be heavy, since that was what the rest of her family was like. They started making small changes like picking healthier options and going for bike rides together. It paid off and the two lost a combined 330 pounds. Now the challenge left is raising money for surgery to remove the excess skin.